Key Eligibility Criteria
- At least 30 years old
 - Current or Former Smoker
 - Living with HIV
 - Emphysema on chest CT scan (can be done as part of screening for the trial)
 
What will happen during the study?
- Involvement in the study is approximately 72 weeks.
 - Screening is done in 3 visits.
 - Study visits after screening will be every 12 weeks.
 
- What will be asked of you:
 - Several Pulmonary Function Tests (PFTs).
 - Two CT scans of the Chest.
 - Blood, urine, and stool collection done throughout the study.
 - Questionnaires asked several times throughout the study.
 
- Participants will be compensated for their time.